Protein Info for DZA65_RS14135 in Dickeya dianthicola ME23

Annotation: glycoside hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 164 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00959: Phage_lysozyme" amino acids 33 to 150 (118 residues), 59.3 bits, see alignment E=2.4e-20

Best Hits

Swiss-Prot: 75% identical to ENLYS_BPP2: Endolysin (K) from Escherichia phage P2

KEGG orthology group: None (inferred from 92% identity to ddd:Dda3937_02796)

Predicted SEED Role

"Phage lysin"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y2P4 at UniProt or InterPro

Protein Sequence (164 amino acids)

>DZA65_RS14135 glycoside hydrolase family protein (Dickeya dianthicola ME23)
MTMLSNPNLIAFLDMLAFSEGTATHPLTRNRGYDVIVTGIDGKPEIFTDYRDHPFSHGRP
AKVFNKQGQRSTAAGRYQQLYRYWPAYKTQLALPDFGPDSQDALAIQLIREQRALDDIMQ
GRLTRAIPRCNNIWASLPGAGYGQREHDAERLVAVYQQAGGKLA