Protein Info for DZA65_RS13520 in Dickeya dianthicola ME23

Annotation: lipoprotein-releasing ABC transporter ATP-binding protein LolD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 TIGR02211: lipoprotein releasing system, ATP-binding protein" amino acids 6 to 225 (220 residues), 356.8 bits, see alignment E=2.1e-111 PF00005: ABC_tran" amino acids 26 to 174 (149 residues), 129.3 bits, see alignment E=1.6e-41

Best Hits

Swiss-Prot: 83% identical to LOLD_PECAS: Lipoprotein-releasing system ATP-binding protein LolD (lolD) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K09810, lipoprotein-releasing system ATP-binding protein [EC: 3.6.3.-] (inferred from 98% identity to ddd:Dda3937_03642)

MetaCyc: 74% identical to lipoprotein release complex - ATP binding subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"Lipoprotein releasing system ATP-binding protein LolD"

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XYX0 at UniProt or InterPro

Protein Sequence (235 amino acids)

>DZA65_RS13520 lipoprotein-releasing ABC transporter ATP-binding protein LolD (Dickeya dianthicola ME23)
MSNSPLLQCRQLCKRYQEGNLSTDVLRDVSFDMQQGEMMAIVGSSGSGKSTLLHLLGGLD
APTSGEVVFQGKALNQLSAAAKAALRNRELGFIYQFHHLLPDFTALENVAMPLLIGNMAP
KEAKEKAQTMLAAVGLAQRSQHRSSELSGGERQRVAIARALVNSPSLVLADEPTGNLDQR
TTDAIFELLGELNVRQGTAFLVVTHDLHLASRLGRQLEMRDGQLQQELTLMGASQ