Protein Info for DZA65_RS11760 in Dickeya dianthicola ME23

Annotation: metal-dependent hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 32 to 48 (17 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 107 to 127 (21 residues), see Phobius details amino acids 147 to 164 (18 residues), see Phobius details PF04307: YdjM" amino acids 1 to 156 (156 residues), 124.4 bits, see alignment E=1.7e-40

Best Hits

Swiss-Prot: 68% identical to YDJM_SHIFL: Inner membrane protein YdjM (ydjM) from Shigella flexneri

KEGG orthology group: K07038, inner membrane protein (inferred from 95% identity to ddc:Dd586_1955)

Predicted SEED Role

"Membrane-bound metal-dependent hydrolase YdjM, induced during SOS response"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CGT5 at UniProt or InterPro

Protein Sequence (192 amino acids)

>DZA65_RS11760 metal-dependent hydrolase (Dickeya dianthicola ME23)
MTAEGHLLFAVASAIFAKKAELSPVLADGDWWHIIPAAMLTALLPDIDHPKSILGQRLKW
ISVPIARLCGHRGFTHSLLAILVGVYVIRTRLPADWPLPGDVYHAMIVGYLSHIVADMLT
TAGVPLLWPCRWRFRLPILNSDKGNQLERLLCVGLILFMLWQPQQPLESWHYGEPARWLQ
QFSQQCRQLLTR