Protein Info for DZA65_RS11655 in Dickeya dianthicola ME23

Annotation: TerC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 47 to 69 (23 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 147 to 147 (1 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details amino acids 183 to 202 (20 residues), see Phobius details amino acids 213 to 231 (19 residues), see Phobius details PF03741: TerC" amino acids 14 to 203 (190 residues), 160.9 bits, see alignment E=4.2e-51 PF00571: CBS" amino acids 299 to 354 (56 residues), 17 bits, see alignment 9.4e-07 amino acids 367 to 416 (50 residues), 21.5 bits, see alignment 3.5e-08 PF03471: CorC_HlyC" amino acids 431 to 507 (77 residues), 53.2 bits, see alignment E=3.6e-18

Best Hits

Swiss-Prot: 74% identical to YOAE_ECO57: UPF0053 inner membrane protein YoaE (yoaE) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_03723)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XZV8 at UniProt or InterPro

Protein Sequence (517 amino acids)

>DZA65_RS11655 TerC family protein (Dickeya dianthicola ME23)
MEFLLDPSIWAGLLTLVILEIVLGIDNLVFIAILADKLPPKQRDKARIIGLSLAMLMRLG
LLSLISWMVTLTRPLFSVGQFSFSGRDLILLAGGVFLLFKATMELHERLENRPHDPNANR
AHASFWAVVVQIVILDAVFSLDAVITAVGMVNHLGVMMTAVVIAMAMMLLASKPLTRFVN
AHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIVIEMFNQIARHNFIKHQS
HRPMRERTAEAILRLMGSRKATHDDQEELPQQQPEETFAEEERYMISGVLTLASRSLRSV
MTPRTDISWVDCERSVEDIRLQLLDTPHSLFPVCRGSLDELVGVVRAKDLLVALDQHTDV
EQFAAANPPIVVPETLDVINLLPVLRRAKGSLVMITNEFGVVQGVVTPLDILEAIAGEFP
DEDETLDIIEDGDGWLVRGGTDLHSLQQVLNVQDLVDPKEDYTSLAGLLLAHSDEFPKVG
DQLKLDRLRFLIVEATDYRIELVRIVRIPETPPVTEV