Protein Info for DZA65_RS11495 in Dickeya dianthicola ME23

Annotation: AvrE-family type 3 secretion system effector

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1634 PF11725: AvrE_T3Es" amino acids 105 to 1625 (1521 residues), 1925.7 bits, see alignment E=0

Best Hits

KEGG orthology group: None (inferred from 90% identity to ddd:Dda3937_02945)

Predicted SEED Role

"Type III effector protein AvrE1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XXI6 at UniProt or InterPro

Protein Sequence (1634 amino acids)

>DZA65_RS11495 AvrE-family type 3 secretion system effector (Dickeya dianthicola ME23)
MLGNINHIQRQQLVTDMQPATAKASHALTQGSAPVSGQSASASLQREGMQARMTPVSQQP
ALPKNEGAQIGRSPNLKDMRPAIDRAMSSASDSSSVAAAPAKDLVSLDKKGRLTPGDGVP
DHLKTLLSETIGKNSLPFVAHQAAKDGSQHVLMDKSGRLFSLQQSGDSLMALHSSTPTQA
AKAGEALSGKNKASYTLGMDDTHVRASIVNRSGVSTINLPQPGQAAQAQLTGVHSDPAHG
NEKLHIHDKALYSLNADQVWEKKSDTPHSQLAGQADGKLYAVKDDKTLTNLSAGHDSAPF
ADKIKSFSANAQGNVAVLTEKGNSTTQLHLLPKADAPAAEHKTLELKLDGNVALARGSEQ
VNAKAVGLTGNLLFVADDEGNVFAGKLPSDGGNAVKLAPYHSPALNAAFGDNHKVQGFVA
GDGGDIHAQVNDAAGQKHLAPLADGSTPGETAGFKPGWNLSDALVVADKTGLNPVRPQPH
DVMDMGRLGTMALHEGKIHYLDSTTQSWSKTDVGASQLKRGLDNQAYVLDDGQVKKLSIN
QKADSVTHGDNNVFAVTQGRNSPSAGDPLPGLEKNSGTTALAVVDGNKFVTANDQGELQL
HLNKPGLQRAAVPPQPLPSAGLSGEVKDLALDKDQNLFALNKDGQLFKLDKQALQGNAEA
RASAQWQPVSTPADVKAEHLSTTKNHEPAISADGHQQHQLTQSGWKTTVPDTQPASSQPR
AAETTYDRLAGVTKAVHIPLTNLTGKVEAQVLGRSGMEGRKLNSNFGDYLGAYVKETAKE
MVRKPVDAAQHHIKGREGLSSVYDTQANMFKKLEQAVSSHTWSPKRDDLQSRMEKLDLGE
AGKPLMAELKSFQNDLEMSAAKSATLLGKHQGVLNNSGEVNEKFKPSVFKAAAQSINDKR
SGKDLSVALSTVMNAAPLSKNSKAGELLNTFVDKKLDMSYQSDKVAAGPHRDLGDAMALT
KSRLALDVMTASSLHGIVDKLDALSGKQPTAADLKPIQAALSELRDHQYGGNDVKKVTDM
GFTHFGALEADYDAVKTFTQAFGNDNSAVRLTSQKSLDAEDKTELAKKLKDTVLSLDNGE
SLAVNRSYNAGASTAYVPKQARVLVHATTFPIIPSGGVTGDRSYSLSFSRGDNGIDVNFG
RNGGLNARVGVATGQAPNDTKKNFDFDDKKHTLALDVRFGGSVTAGVGTVQQNGLKFTLN
EKELPGFVDKLIEGKVNPLDLVTKGNDHRVKEGFSIKFDLDAALTADARAEVNLADKPSA
AQRGKVPTSAGRLSVGVGAGANLMSASHEHSTVRGEFTEQNATTNNRVRFMNQVNVGANA
TAFAGITKPDPNGSWTAPLSSNASVTMTVDTKTNHSISMQLKAAQPLEGRDMDSLLSSLE
KKFTDPETQQVLKGVKDLTDTGEKLAILNKHFEAKTPADDGQYGAIRDLQAKTRQHEAAE
KQGVTLDSASYSTSYANLSKLDSNGIFHALRKLVSDNLPPTNAERIHGFMEENPALKAVV
QKMQSLTNATAGVSLELKDEVKAKVEQGIQNNTMGKDDIAAIFRDSNNLRIKSVDFTQTV
KNKEGLAFPLPIVSAGSSADVSMTKLLGKINFSYGQNQDSPGSFSLEGAIARANSDVSQA
VNQMHQQGITLAKH