Protein Info for DZA65_RS11280 in Dickeya dianthicola ME23

Annotation: GMC family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 612 transmembrane" amino acids 583 to 596 (14 residues), see Phobius details PF00890: FAD_binding_2" amino acids 15 to 51 (37 residues), 21.1 bits, see alignment 3.2e-08 PF13450: NAD_binding_8" amino acids 18 to 47 (30 residues), 23.5 bits, see alignment (E = 1.1e-08) PF00732: GMC_oxred_N" amino acids 264 to 369 (106 residues), 25.8 bits, see alignment E=1.8e-09 PF05199: GMC_oxred_C" amino acids 462 to 592 (131 residues), 57 bits, see alignment E=6.4e-19

Best Hits

KEGG orthology group: None (inferred from 95% identity to ddd:Dda3937_01643)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XYE4 at UniProt or InterPro

Protein Sequence (612 amino acids)

>DZA65_RS11280 GMC family oxidoreductase (Dickeya dianthicola ME23)
MNVITPHQAEQTDYDVVIVGGGIAGSLMAKTLTRGGKRCLILEAGDGENLHYAGYRQTLQ
RYRQHPGKSHQVSGPRNVNAPAPHDAALQPLMPDGYDDRGYLVQRGPLPFSSTYCRQLGG
TSLQWLGSAMRMLPEDFELQSRYGIGLDWPLRYNDLEPWYRAAEYELGVSANVAEQAYLG
IRFPPDYVYPMQGLPPAWGDRQLARRLNGMTVMEDGQATPLTLCGTPSARNGVPHPGYDH
GRGYHPRGAAGSPQLGLRCSGNSHCTPFCPTQARYNALKTLEDADPALLDVVTCSVAHKL
LIDPSTDAITGIQFRHYVHQETALHHLHTVRARRYVLAGNAIANAVLLLASDACKGNDLV
GRHLMDHPVLPVWGRADAPLWPMRGPLTTSGIEAMRGGSARAHRAAYRIELSNDGWRWPV
NALYHDVEQLLAEPLCGPRLRSQLRERLLRQFSARCLVEQLPEYNNRVTIHPDYRDALGN
YRPVIHYDLALYTRTGVARAGTVMRQIFRHAGIRDHSHYSPADPGYFTCQGQPLAFVGAG
HIAGTHCMGKSPHHSVVDRQQRSWIHKNLYLVGAGNMVSMGTAPPTLTLAALTLWAAHTI
LSELDRMCASTR