Protein Info for DZA65_RS11135 in Dickeya dianthicola ME23

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 transmembrane" amino acids 32 to 57 (26 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 101 to 120 (20 residues), see Phobius details amino acids 126 to 147 (22 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 208 (22 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 267 to 288 (22 residues), see Phobius details amino acids 302 to 351 (50 residues), see Phobius details amino acids 365 to 384 (20 residues), see Phobius details amino acids 390 to 408 (19 residues), see Phobius details PF07690: MFS_1" amino acids 39 to 258 (220 residues), 106.1 bits, see alignment E=2e-34 PF00083: Sugar_tr" amino acids 69 to 215 (147 residues), 46.3 bits, see alignment E=2.9e-16

Best Hits

Swiss-Prot: 73% identical to YNFM_ECOLI: Inner membrane transport protein YnfM (ynfM) from Escherichia coli (strain K12)

KEGG orthology group: K08224, MFS transporter, YNFM family, putative membrane transport protein (inferred from 97% identity to ddd:Dda3937_04128)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XY34 at UniProt or InterPro

Protein Sequence (416 amino acids)

>DZA65_RS11135 MFS transporter (Dickeya dianthicola ME23)
MSISVTDDIQPQRNTHAPVYKNPFITRGTPTFIRVTLALFSAGLATFALLYCVQPILPVL
SQAFGVSPATSSLSLSVSTITMAVGLLFTGPLSDTVGRKNVMVVSLLLASVCTLIGSMMT
NWAGLLAMRALVGLSLSGVAAVAMTYLSEEIHPSVVAFSMGLYISGNSIGGMSGRLLTGV
ITDFFNWRVSIACIGVVALLASLTFWRILPDSRHFRAGSLRPKTLWINVRLHWRDAGLPL
LFAEGFLLMGTFVTLFNYIGYRLLGAPYNLSQTVVGLLSVVYLTGSYASPRAGAMIARFG
RGSVLVGSVALMLSGLLLTLFSSLLVMFAGMMLFAAGFFAAHSVASSWIGVRALRARGQA
SSQYLFCYYLGSSLAGTSGGFFWYHYGWTGLVLFLSCLLMLALLLGFKLKSLKNRV