Protein Info for DZA65_RS10825 in Dickeya dianthicola ME23

Annotation: two-component system response regulator RssB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 PF00072: Response_reg" amino acids 10 to 117 (108 residues), 97.1 bits, see alignment E=3.6e-32

Best Hits

Swiss-Prot: 64% identical to RSSB_ECOLI: Regulator of RpoS (rssB) from Escherichia coli (strain K12)

KEGG orthology group: K02485, two-component system, unclassified family, response regulator (inferred from 94% identity to dze:Dd1591_2201)

Predicted SEED Role

"Hnr protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CD33 at UniProt or InterPro

Protein Sequence (338 amino acids)

>DZA65_RS10825 two-component system response regulator RssB (Dickeya dianthicola ME23)
MAQPLTGKHILVVEDEAVFRSVLAGYLTSLGADVHEADNGKDALEKMAHQSPDLIICDLN
MPLMGGFEFVERLRLHDITTPVLVVSATNHLADIARVLRLGVQDVLLKPIHDYTRLRESV
MACLYPTMFTSQANEVEQLMHDLDTLNQSPGAASKLLEQLQPPVQQTLARCRVNYRQLMA
VDRPGLVLDIAALSGDELAFYCLDVTQAANNHGVLAALLLRALFNSLLQEHLVHQQRRLP
ELPVLLNQVNQLLRRANLQGRFPLLVGYYHRELKRLILISAGLHATLSVEEQHIGLNNGV
PLGTLEAAYLNQISYQCESWQCQMWGSGGRLRLMLSTD