Protein Info for DZA65_RS09920 in Dickeya dianthicola ME23

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1176 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details PF13491: FtsK_4TM" amino acids 20 to 191 (172 residues), 157.7 bits, see alignment E=4.7e-50 PF17854: FtsK_alpha" amino acids 686 to 786 (101 residues), 101.7 bits, see alignment E=4.5e-33 PF01580: FtsK_SpoIIIE" amino acids 794 to 1007 (214 residues), 280.1 bits, see alignment E=2.3e-87 PF09397: FtsK_gamma" amino acids 1111 to 1171 (61 residues), 93.1 bits, see alignment 1.4e-30

Best Hits

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 90% identity to ddd:Dda3937_00129)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CUT3 at UniProt or InterPro

Protein Sequence (1176 amino acids)

>DZA65_RS09920 DNA translocase FtsK (Dickeya dianthicola ME23)
MSQEYTEDKDVTLKKLSAGRRLLEAMLIVVVLFAIYLAVALLSFSPSDPSWSQTAWHEPI
HNLGGGVGAWLADTLFFIFGVLAYAIPVVMASLCWVIHRQRGQRATLDYFALSLRLIGTL
ALILTSCGLAALNVDDIYYFASGGVLGSLLSSSMVPRFNNIGATMILLCVWAAGLTLFTG
WSWLTIAEKLGAGVMGCLTLFSGRRREDDYLYDDDDEEIDESSAAARKEAHRTAAPHEDE
PAAVLSAVSVSSSAEVDNDDDDALFSAPGVTATSGAAAVEMPVVNQANERAFATTATPDA
EPVLKPHPEPIAVTPLAGPESFVPPVAAPVPEFRPGADVSPASPLAPAGIVPASADFAPS
LSEPLPDWQPLTLQADDRIARTAAAAVTAATVVAGNAGAATEPKPESQNATLFMPAFTTD
EDNNPQVKRGMGPELPRPNPVRIPTRRELASYGIKLPSQRLAEQQAREAEQQAQSAHVEP
TGALTPFAAQTPLPDMPNDETAQTALPDDDQDTLIQEAALRQAFADQQRERYGETYPDHE
EAEETLLQAQLARDFAAMQRSRYTAHGPDTEQDAPAIFAAESPTVTPAAAETTAFGMKPR
ADAPLDSAFAISPFADLVEDGPLEPLFTLPPQERFPDEPQYAPALQTAAPIEPEAEAESS
SSMMDSLIHPFLMRNDQPLHKPTTPLPSLDLLTPPSMNDAPVDRDVLDDMARLIETRLAD
YRVKATVVDYHPGPVITRFELDLAPGVKAARISNLARDLARSLSVVAVRIVEVIPGKPYV
GLELPNRHRQTVFLREVLDCDRFRDNASPLAIVLGKDISGQPVVADLAKMPHLLVAGTTG
SGKSVGVNAMIISMLYKATPADVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALR
WCVGEMERRYKLMSALGVRNLSGYNERVMQAEAMGRPVPDPFWKPGDSMDAQPPVLEKLP
YIVVMVDEFADLMMAVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPT
RIAFTVSSKIDSRTILDQGGAESLLGMGDMLYMAPNSSIPIRVHGAFVRDQEVHAVVQDW
KARGRPEYIDNIISGDDDGEGGSLGFDGDEDLDPLFDQAVAFVVEKRRASISGVQRQFRI
GYNRAARIVEQMEMQGIVSSPGHNGNREVLAPPPME