Protein Info for DZA65_RS09900 in Dickeya dianthicola ME23

Annotation: cysteine/glutathione ABC transporter ATP-binding protein/permease CydC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 transmembrane" amino acids 15 to 37 (23 residues), see Phobius details amino acids 41 to 70 (30 residues), see Phobius details amino acids 91 to 113 (23 residues), see Phobius details amino acids 133 to 155 (23 residues), see Phobius details amino acids 162 to 183 (22 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 278 to 299 (22 residues), see Phobius details TIGR02868: thiol reductant ABC exporter, CydC subunit" amino acids 6 to 533 (528 residues), 511.4 bits, see alignment E=1.4e-157 PF00664: ABC_membrane" amino acids 94 to 287 (194 residues), 30.9 bits, see alignment E=3.4e-11 PF00005: ABC_tran" amino acids 356 to 502 (147 residues), 108.3 bits, see alignment E=7.5e-35

Best Hits

Swiss-Prot: 65% identical to CYDC_ECOLI: ATP-binding/permease protein CydC (cydC) from Escherichia coli (strain K12)

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 95% identity to ddd:Dda3937_04326)

MetaCyc: 65% identical to glutathione/L-cysteine ABC exporter subunit CydC (Escherichia coli K-12 substr. MG1655)
7.4.2.-; 3.6.3.M9 [EC: 3.6.3.M9]

Predicted SEED Role

"Transport ATP-binding protein CydC" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.M9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XWK3 at UniProt or InterPro

Protein Sequence (578 amino acids)

>DZA65_RS09900 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC (Dickeya dianthicola ME23)
MQVLKPFLALYRRHLFRLGLGVVLAILTLLASIGLLTLSGWFLAASAVAGLVGLTTFNYM
LPAAGVRGAAILRTASRYFERLVSHDGTFRVLLHLRVFTFSRILPLAPGGLSGFRQADLL
NRLVADVDTLDHLYLRVISPLVSALAVILALAYGLSWLDASLALTLAAIMLALLLLLPLT
FYRAGQPVGADLTTLRAHYRVQLTTWIQGQAELAVFGALAHFRQQLEILEQRWFKRQRQQ
AELGALSQSILIAAGGLTATLLLWLAAGGVGGDQQPGALIALFVFTSLAAFEALAPVAGA
FQHIGQVVASAARVDQLLKLRPPVTFASQGPARLEQVQLTLDKVSFTYPEQNQPALSEIS
LTLAPGEHIALLGRTGCGKSTLLQLLTRAWDCSAGEIRLNDTPIAAYTEPTLRDAMSVVP
QRAHIFSATLRENLRLAAPAASDERLQTVLAQVGLEKLLEDQGLNAWLGEGGRQLSGGEQ
RRIGVARALLHPAPLVLLDEPTEGLDADTEQRILQLLRQHCLGKSLIVITHRLNGLESMD
RLCVMDGGQLVEQGSHHSLMALQGRYWQFHQHLFHQHL