Protein Info for DZA65_RS09700 in Dickeya dianthicola ME23

Annotation: DUF418 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 64 to 84 (21 residues), see Phobius details amino acids 91 to 109 (19 residues), see Phobius details amino acids 115 to 132 (18 residues), see Phobius details amino acids 142 to 160 (19 residues), see Phobius details amino acids 204 to 223 (20 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details amino acids 314 to 335 (22 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details PF04235: DUF418" amino acids 222 to 380 (159 residues), 143.3 bits, see alignment E=3.6e-46

Best Hits

Swiss-Prot: 58% identical to YEIB_ECOLI: Uncharacterized protein YeiB (yeiB) from Escherichia coli (strain K12)

KEGG orthology group: K07148, uncharacterized protein (inferred from 91% identity to ddd:Dda3937_03496)

Predicted SEED Role

"FIG00924762: possible membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XWH0 at UniProt or InterPro

Protein Sequence (395 amino acids)

>DZA65_RS09700 DUF418 family protein (Dickeya dianthicola ME23)
MSSPPHSSSRIPMLDFARGLAVLGILLMNIVSFGLPHAAYLNPAWQGPPAAADAWTWALM
DMVAQGKFLTLFALLFGAGLQLLLKRGKRWIHARLFWLMVLGLLHSLFWWDGDILLDYGL
IGLVCFGLLQHAGSTRMLLRTGVVLYLMGLAMLVVLSQVLSPDGGSFWQPGPAEVEYEAW
WLTQGGPEAWHNRLSLLNESLLSLGIQYGWLLAGSMLMGAALMRSGWLRGQFSQRHYRRI
ALWLLPLALLINALGVMAQWHLQWEYRWCGLLLQIPREVSAPLQAMAYLALCYGFWPALA
NWRLTRWVVDVGRMALSSYLLQTLICTALFNRLGWFMQLDRWQLLLVVPPVWLCNLLAAR
IWLSVFRQGPVESVWRWLTARVAGPVQHNPRSNPD