Protein Info for DZA65_RS09235 in Dickeya dianthicola ME23

Annotation: 5-oxoprolinase subunit PxpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 PF03746: LamB_YcsF" amino acids 5 to 242 (238 residues), 291.6 bits, see alignment E=2.5e-91

Best Hits

Swiss-Prot: 66% identical to PXPA1_PSEAE: 5-oxoprolinase subunit A 1 (pxpA1) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K07160, UPF0271 protein (inferred from 95% identity to ddd:Dda3937_02459)

Predicted SEED Role

"Lactam utilization protein LamB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4C5D1 at UniProt or InterPro

Protein Sequence (260 amino acids)

>DZA65_RS09235 5-oxoprolinase subunit PxpA (Dickeya dianthicola ME23)
MKYEIDLNSDMGENFGPWKIGDDVDQEIMSYISSANIAAGFHAGDPTTIRQTIEWASDYG
VAVGAHPGFRDLVGFGRRHIHSQPQEVVNDILYQLGALREFTRLYQLPLQHVKPHGALYM
HLARDQPSAQLFVETLHRLDPELRLFCLHGSWAWQEAKKLQHPVICEFYGDREYDASGSI
VFARRVGELDPARVAAKVVRACVEGNVTTVDGEDIHVEFESICIHSDTPGALALIKTTRE
ALNNANIRVRSPLRNSVNYR