Protein Info for DZA65_RS08600 in Dickeya dianthicola ME23

Annotation: type VI secretion system protein TssA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 TIGR03362: type VI secretion-associated protein, VC_A0119 family" amino acids 6 to 472 (467 residues), 479.2 bits, see alignment E=8.5e-148 PF06812: ImpA_N" amino acids 13 to 111 (99 residues), 61.8 bits, see alignment E=6.9e-21 PF16989: T6SS_VasJ" amino acids 227 to 471 (245 residues), 282 bits, see alignment E=4.6e-88

Best Hits

KEGG orthology group: K11910, type VI secretion system protein VasJ (inferred from 92% identity to ddd:Dda3937_00805)

Predicted SEED Role

"Uncharacterized protein ImpA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4DC53 at UniProt or InterPro

Protein Sequence (478 amino acids)

>DZA65_RS08600 type VI secretion system protein TssA (Dickeya dianthicola ME23)
MHAHPWCKRLLTALPDDALRAAVAADDPLWEKVETALVKLGSLAHSQVDLNAVAGQCLTL
LESRTKDMRVLVQLLRCLQHPAKATPFATAIMLLDSWLEAYWTLAFPASAVQKQKLMVQI
IRRFEGVLPRVAENASGAELSQLHQLAEQLAARWRTLAADKAELTDELAASLHRARQRHQ
AQEKANQAAEPASGGPGGTSGGDAAAGGGNGGSGTASAAATVDINSSDDRHWKQTQLTVA
ALLAERQPEAPVGYRLRRNAVWAGIATPPPAARGNKTQLAPVSPDRVDEYHSALAQADLA
LWNKIEQSLTLAPYWFDGHLLSATVATRLGHSAVAGAIADELSAFLARLPELRELAFSDG
SPFLSAKCAQWLQSAQSARGGGGQRQDDLAAEAAACCAEQGLGAALSLLDERIRRLKEPR
ERFCAELVLADLLAEEGMKALAAQHYQHLWQESERLGLMQWEPGMVSRLERLGASRRK