Protein Info for DZA65_RS08585 in Dickeya dianthicola ME23

Annotation: type VI secretion system ATPase TssH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 878 TIGR03345: type VI secretion ATPase, ClpV1 family" amino acids 13 to 866 (854 residues), 1165.3 bits, see alignment E=0 PF00004: AAA" amino acids 220 to 332 (113 residues), 33.6 bits, see alignment E=2e-11 amino acids 609 to 726 (118 residues), 26.4 bits, see alignment E=3.3e-09 PF17871: AAA_lid_9" amino acids 360 to 451 (92 residues), 101.7 bits, see alignment E=8.1e-33 PF07724: AAA_2" amino acids 603 to 776 (174 residues), 170.8 bits, see alignment E=1.1e-53 PF07728: AAA_5" amino acids 608 to 726 (119 residues), 38.2 bits, see alignment E=5.6e-13 PF10431: ClpB_D2-small" amino acids 782 to 854 (73 residues), 31.8 bits, see alignment E=4.6e-11

Best Hits

KEGG orthology group: K11907, type VI secretion system protein VasG (inferred from 96% identity to ddd:Dda3937_00808)

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CX77 at UniProt or InterPro

Protein Sequence (878 amino acids)

>DZA65_RS08585 type VI secretion system ATPase TssH (Dickeya dianthicola ME23)
MIRIELPVLVERLNPLCRHMMEDAAALCVQHQGAEIRIEHLLLKMLETPLCDVRQILKRA
GMDADELAALLQPHAADNGFESGYPSFSPLLVEWLQDSWLLASAELQHARLRSGVLLLVL
LMTPTRYLSATVTRQLAQINRELLRQQFDEWVKDSAETEVIAAAGATPEQAAAATTQLSR
YTQNVTESARQGTLDPVLCRDHEIDLMIDILSRRRKNNPIVVGEAGVGKSALIEGLALRI
VAGLVPERLRDVELLTLDLGAMQAGASVKGEFEKRFKGVMQEVKEAPKPVVLFIDEAHTL
IGAGNQAGGLDVSNLLKPALARGELRTIAATTWSEYKKYVEKDAALSRRFQLVKVSEPNV
DDATVILRGLRSIYEQSHGVLIDEEALQAAANLSARYISGRQLPDKAIDVLDTACARVAI
NLTTPPRAVSQLQTRLHQQALEIAQLERQGRIGLGDTAARLAALREARETDAATLAQLEA
DWQRQKTLVQQIVALRTALLADEAPEAFDAAAAAAALADSERALAELQQPSVLVSPHVDK
TQIASVIAEWTGVPLNRISQGELDVVTRLPDYLGDSIKGQQLAIAQLHKHLLTARADLRR
PGRPLGAFLLVGPSGVGKTETVVQIADLMFGGRHYLTTINMSEYQEKHTVSRLIGSPPGY
VGFGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGELADGEGRVIDCRNVV
FFLTSNLGFQTIVNFAEHVSFAEHVSFADRQNDLLDALYPELAAFFKPALLARMEVIPYL
PLGNDTLVAIVQGKLSRLVTLLQQRFGAEVVIDASVPEAILRLANRSENGARMLESVIDG
ALLPPVSLQLLQRLSAGQPVSRIHFRVEDGQFRSEVEG