Protein Info for DZA65_RS06770 in Dickeya dianthicola ME23

Annotation: potassium-transporting ATPase subunit KdpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 219 to 243 (25 residues), see Phobius details amino acids 255 to 281 (27 residues), see Phobius details amino acids 584 to 605 (22 residues), see Phobius details amino acids 620 to 641 (22 residues), see Phobius details amino acids 661 to 685 (25 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 3 to 683 (681 residues), 1137.2 bits, see alignment E=0 TIGR01494: HAD ATPase, P-type, family IC" amino acids 72 to 333 (262 residues), 113.3 bits, see alignment E=1e-36 amino acids 378 to 610 (233 residues), 158.5 bits, see alignment E=2e-50 PF00122: E1-E2_ATPase" amino acids 114 to 288 (175 residues), 107 bits, see alignment E=1.3e-34 PF00702: Hydrolase" amino acids 307 to 536 (230 residues), 96 bits, see alignment E=5.9e-31 PF08282: Hydrolase_3" amino acids 507 to 555 (49 residues), 22.2 bits, see alignment 1.6e-08

Best Hits

Swiss-Prot: 84% identical to KDPB_SERP5: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Serratia proteamaculans (strain 568)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 98% identity to ddd:Dda3937_01550)

MetaCyc: 80% identical to K+ transporting P-type ATPase subunit KdpB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CAE4 at UniProt or InterPro

Protein Sequence (688 amino acids)

>DZA65_RS06770 potassium-transporting ATPase subunit KdpB (Dickeya dianthicola ME23)
MIRKQQTLFDAALLRNALVDSVKKLSPRIQWRNPVMFVVYIGSLLTAGIWLAIVSGQTAG
NAGFTGAVSLWLWVTVLFANVAEALAEGRSKAQAETLKGVKKTSWANKLAAPHHDAASQK
APADSLRKGDVVLVSAGEMIPCDGEVLEGGASVDESAITGESAPVIRESGGDFASVTGGT
RVLSDWLVIQCTVNPGETFIDRMIAMVENAKRRKTPNEVALTILLVELTIIFLLVVATLS
PFSWFSVTANNSGSVISITVLVALLVCLIPTTIGGLLSAIGIAGMSRMLGANVIATSGRA
VEAAGDIDVLLLDKTGTITLGNRQASAFLPAPGVSEQALADAAQLASLADETPEGRSIVV
LAKQRFGLRERALRDLDATFVPFSAQTRMSGVNIQERTIRKGAVDALRRYIDANQGQFPA
EVEDAVAGVARQGGTPLVVAEGKRVLGVVALKDIVKGGIKERFAELRSMGIKTVMITGDN
PLTAAAIAAEAGVDDFLSEATPEAKLALIRQYQAEGRMVAMTGDGTNDAPALAQADVAVA
MNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAA
FAATYPQLNALNVMQLHSPASAMLSAVIFNALIIVFLIPLALKGISYKPMSAAALLSRNL
WIYGLGGLLVPFAGIKLIDLFLTVAGLA