Protein Info for DZA65_RS06235 in Dickeya dianthicola ME23

Annotation: NfeD family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 transmembrane" amino acids 12 to 42 (31 residues), see Phobius details amino acids 54 to 73 (20 residues), see Phobius details PF01957: NfeD" amino acids 60 to 148 (89 residues), 79 bits, see alignment E=1.5e-26

Best Hits

Swiss-Prot: 62% identical to YBBJ_SHIFL: Inner membrane protein YbbJ (ybbJ) from Shigella flexneri

KEGG orthology group: K07340, hypothetical protein (inferred from 99% identity to ddd:Dda3937_04161)

Predicted SEED Role

"Putative activity regulator of membrane protease YbbK" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XUY5 at UniProt or InterPro

Protein Sequence (150 amino acids)

>DZA65_RS06235 NfeD family protein (Dickeya dianthicola ME23)
MMMALVLENAHWFWLSLGGLLLAAEMLGAGGYLLWSGIAALLTGILAWLLPLDWTWQCIA
FAVLTVAAALLWWQWLRRRIEKQPPPVLNQRGQQLIGLHTTLTEPLVNGFGRVNIGDSSW
RVQAEQDLPAGTVVEIIAVEGITLRVRPRT