Protein Info for DZA65_RS06035 in Dickeya dianthicola ME23

Annotation: competence protein ComEA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 124 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF12836: HHH_3" amino acids 60 to 123 (64 residues), 72.3 bits, see alignment E=4.4e-24 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region" amino acids 61 to 122 (62 residues), 97.5 bits, see alignment E=1.8e-32 PF00633: HHH" amino acids 64 to 91 (28 residues), 24.1 bits, see alignment 3.6e-09 PF03934: T2SSK" amino acids 65 to 112 (48 residues), 31.2 bits, see alignment E=3.6e-11

Best Hits

Swiss-Prot: 48% identical to YBAV_SHIFL: Uncharacterized protein YbaV (ybaV) from Shigella flexneri

KEGG orthology group: K02237, competence protein ComEA (inferred from 90% identity to ddd:Dda3937_03315)

Predicted SEED Role

"FIG01200701: possible membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CCX5 at UniProt or InterPro

Protein Sequence (124 amino acids)

>DZA65_RS06035 competence protein ComEA (Dickeya dianthicola ME23)
MKKSGIKALCLIVGMSFSGVSTWLHASPAVTTPDKPGIAAVKPASPEQKLEKATRSATDE
EEVSINTATAEQLAAALNGVGLKKAQAIVSYREQNGPFTQLEQLQEVPGIGNALIERNQS
HLRL