Protein Info for DZA65_RS05500 in Dickeya dianthicola ME23

Annotation: molecular chaperone Skp

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03938: OmpH" amino acids 25 to 163 (139 residues), 113 bits, see alignment E=6.9e-37

Best Hits

Swiss-Prot: 89% identical to SKP_PECAS: Chaperone protein Skp (skp) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K06142, outer membrane protein (inferred from 99% identity to dze:Dd1591_3156)

MetaCyc: 66% identical to periplasmic chaperone Skp (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Outer membrane chaperone Skp (OmpH) precursor @ Outer membrane protein H precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CI53 at UniProt or InterPro

Protein Sequence (165 amino acids)

>DZA65_RS05500 molecular chaperone Skp (Dickeya dianthicola ME23)
MKKWLYAAGLGLTLAVSAGAQAADKIAIVNVSSIFQQLPQREAVGKQLENEFKGRASELQ
SMERALQEKMQKLQRDGSTMKASERSKMESDVMAQREQFSSKAQAFDQDNRRRQMEERNK
ILSRIQDAVKAVATKQGYDVVIDANAVAYADNAKDITADVLKQVK