Protein Info for DZA65_RS05395 in Dickeya dianthicola ME23

Annotation: DUF423 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 128 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 23 to 24 (2 residues), see Phobius details amino acids 43 to 61 (19 residues), see Phobius details amino acids 68 to 91 (24 residues), see Phobius details amino acids 97 to 121 (25 residues), see Phobius details PF04241: DUF423" amino acids 20 to 106 (87 residues), 85.5 bits, see alignment E=1.2e-28

Best Hits

Swiss-Prot: 75% identical to YGDD_ECOLI: UPF0382 inner membrane protein YgdD (ygdD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to ddd:Dda3937_00868)

Predicted SEED Role

"COG2363"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D733 at UniProt or InterPro

Protein Sequence (128 amino acids)

>DZA65_RS05395 DUF423 domain-containing protein (Dickeya dianthicola ME23)
MNSRFMLIFAAISGFVYVALGAFGTHVLSKSLGEAEMSWLHTGLQYQAFHTLAILALSVA
MHQRANVWFYWSAALLALGTLLFSGSLYCLALSHLKLWVFVTPVGGVCFLTGWLLLLIGA
LRLKKKAE