Protein Info for DZA65_RS04560 in Dickeya dianthicola ME23

Annotation: molybdopterin-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 753 transmembrane" amino acids 334 to 354 (21 residues), see Phobius details PF18364: Molybdopterin_N" amino acids 8 to 48 (41 residues), 64.1 bits, see alignment 1.4e-21 PF00384: Molybdopterin" amino acids 52 to 507 (456 residues), 161 bits, see alignment E=6.5e-51 PF01568: Molydop_binding" amino acids 625 to 746 (122 residues), 95.9 bits, see alignment E=2.4e-31

Best Hits

KEGG orthology group: K08351, biotin sulfoxide reductase [EC: 1.-.-.-] (inferred from 92% identity to ddc:Dd586_0856)

Predicted SEED Role

"Anaerobic dimethyl sulfoxide reductase chain A (EC 1.8.5.3)" (EC 1.8.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.-.-.-

Use Curated BLAST to search for 1.-.-.- or 1.8.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XYN0 at UniProt or InterPro

Protein Sequence (753 amino acids)

>DZA65_RS04560 molybdopterin-dependent oxidoreductase (Dickeya dianthicola ME23)
MTIRRYPHLAHWGAFTAVVEGGRLIRCEPFAGDADPSPMLDSIAPLVYSDKRIRKPAVRR
SWLEKRENSDRTLRGKEPFVEVDWDRALDLVAEENRRVRDRYGADGLFAGSYGWSSAGRF
HHARSQVRRFYFSGGGAVDQTGNYSWGAAQFFLPYVIGTFHPLTGKVTEWRSVAEHCELF
LAFGGLALKNAQVASGGAGHHTLKPALEKLAARGTPIINISPMRDDCPAFVNAEWIPIRP
NTDVALMLALGYQIQQLGAEDHDFLDRHCVGYPQLHDYLNGRTDGIAKNPVWASAITGIP
AARIEKLAQQLIGVRSFMTCSYSVQRAHRGEQPYWMMIALASMLGQVGLPGGGFSFGHGS
MNSVGNERMTSPAPASPSVPNPGQSIPVARIADMLLHPGEPYTFCGENRTYPDIHLIHWA
GGNPFHHHQQLNRLVEGWQRPDTVIVQDIVWTAAAQMADIVLPVTTSLERNDVGGSSRDR
FVFAMHQAITPQHQARNDYDIFSELAQRLGYGDAFTHDGRTERQWLESMYLACRERQGTA
GELWPDFDRFWQQGYVDIPMDDQPFVFFDEFRRDPARHPLNTPSGKIELFSRTIADYRYP
DFAPHPQWQPPVEWLGAAETQRWPLHFISIQPADRLHSQLGCTPQVAANKTAGHETLYMH
SQDASARGIRHGDRVEVRNERGRIYAGVDVTDGVTPGVVIMATGAWFDPGFGQAQWRPVE
QSGNANVLTRDMGTSPLTQGPNAMSCLVEVLAL