Protein Info for DZA65_RS04490 in Dickeya dianthicola ME23

Annotation: ribonuclease Z

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 PF00753: Lactamase_B" amino acids 25 to 120 (96 residues), 38.8 bits, see alignment E=1e-13 PF12706: Lactamase_B_2" amino acids 30 to 200 (171 residues), 54.8 bits, see alignment E=1e-18

Best Hits

KEGG orthology group: None (inferred from 92% identity to ddd:Dda3937_01453)

Predicted SEED Role

"Ribonuclease Z (EC 3.1.26.11)" in subsystem tRNA processing (EC 3.1.26.11)

Isozymes

Compare fitness of predicted isozymes for: 3.1.26.11

Use Curated BLAST to search for 3.1.26.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XTX8 at UniProt or InterPro

Protein Sequence (255 amino acids)

>DZA65_RS04490 ribonuclease Z (Dickeya dianthicola ME23)
MELEILGSGEAYDSQRVNAAIRVSEGGFQLLVDCGPTVPQALWQRRTAPDDIHAIYITHA
HPDHALGLTSWLNWCESGGRTAPLAIIAPRQQLPQVQRLADFAFWPAGRPLFTLNWQDSE
SLSELGPWRCQTAPTRHSVPNRSLYLNGEQGSLFYSGDGQLTPAGAALLAQADLALVECF
SPQAADNAYHGNWPQVQTLARKPGAPLGLYHVQQSQKAALQQVIAAASGVFLPEQGDRAH
CRHGRWHLIRDSEHE