Protein Info for DZA65_RS03460 in Dickeya dianthicola ME23

Annotation: tRNA-modifying protein YgfZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 TIGR03317: folate-binding protein YgfZ" amino acids 187 to 251 (65 residues), 89.5 bits, see alignment E=5.3e-30 PF21130: YgfZ_barrel" amino acids 243 to 310 (68 residues), 121.9 bits, see alignment E=4.5e-40

Best Hits

Swiss-Prot: 72% identical to YGFZ_PECCP: tRNA-modifying protein YgfZ (PC1_0637) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K06980, (no description) (inferred from 94% identity to ddd:Dda3937_02302)

Predicted SEED Role

"Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CGQ6 at UniProt or InterPro

Protein Sequence (326 amino acids)

>DZA65_RS03460 tRNA-modifying protein YgfZ (Dickeya dianthicola ME23)
MAHPFTAQPLFSSAQLPATLISLDDWALVTLAGPDTVKYLQGQLTADVDALQASQHVLCA
HCDAKGKMWSNVRLFHYGDGLAYLERRSVRDTQLAELKKYAVFSKTTIAADDNVVLLGAA
GLDIRAQLAPLFDALPDADNAVVRQPGATLLYLPHPAERFLLVLEAQRAAALIETLQPRV
QHNDSRQWQALDIAAGQPIIDSANSAQFIPQATNLQALQGISFTKGCYAGQEMVARAKYR
GANKRALYWLAGTGAQAPTAGDELEWKLGDNWRRTGTVLAASQLHDGTLWVQAVLNNDLE
ADNVLRVRDDSGSQLAIQPLPYSLEE