Protein Info for DZA65_RS03370 in Dickeya dianthicola ME23

Annotation: type I restriction endonuclease subunit R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1034 PF04313: HSDR_N" amino acids 3 to 177 (175 residues), 99.2 bits, see alignment E=4.6e-32 PF04851: ResIII" amino acids 286 to 458 (173 residues), 80.4 bits, see alignment E=2.2e-26 PF18766: SWI2_SNF2" amino acids 291 to 506 (216 residues), 127.4 bits, see alignment E=1.1e-40

Best Hits

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XTZ3 at UniProt or InterPro

Protein Sequence (1034 amino acids)

>DZA65_RS03370 type I restriction endonuclease subunit R (Dickeya dianthicola ME23)
MKFTEDTRVKIPTILHLMKLGYHYLPLKEQSWDKDTNIFPDIFTSAIARINPTILPDDIG
RLFKDIKLLLDNEDLGRAFFEKLTDRSNVKLIDFENFNNNSFHVVTELTCANGDEEFRPD
ITLLINGMPLVFIEVKKPNNREGILAERERISKRFQNPKFRRFANITQFMIFSNNMKYDN
SDPEPIQGAFYASSSYHEPVFNYFREEETFDLTALLKPLTDDAELKVLKDNNLEVIRTSP
EFQTNKDYNRPTNRICTSLLSRERLAFILRYALVYVTESDGLHKHIMRYPQLFATKAIAR
KLNAGINKGIIWHTQGSGKTALAYYNVQFLTDYFQQKQVIPKFYFIVDRLDLLQQAHREF
TARGLTVHQVNSRSAFARAIKATQVLHNHQGKAEITVVNIQKFKDDANVIATQDYDVNIQ
RVYFLDEVHRSYNPEGSFLANLSQSDTHAIKIGLTGTPLLGTDYNSRDLFGGYLHKYYYN
ASIADGYTLRLIREEIATNYRMVLQQALKDVEVRMGDVDRKQVYAHVSFVKPMLDYITTD
FANSRGALNDDTIGGMVICDSSEQAKQMFALFNASHADDAPPPAMLKAENEITPAHAAEP
SAAYTATTREKRSIKRAALILHDVGTKQQRKDWVDEFKAGKIDLLFVYNMLLTGFDAKRL
KKLYLGRVIRRHNLLQALTRVNRPYKHFRYGYVVDFADIRQEFDATNKAYFEELQSELGD
EMEHYSRLFKSQEEIRQEIEQIKDVLFHFDTDNAEVFADQINQIQDRKTALALKNALANA
RSLYNLIRLQGNVEFLQALDFNKLNLLYREASNHLDLLNLKADLEQGADTSNLLNRALEE
VIFKFVKIGEEELVLADKLKDTLRRTREALASNFDPQDPQFITLKEELERLFKKKKLSDV
TQDEMVANISTLNKIHDRIKELNRQNTLLRQKYRGDAKYARTHKRLQERGGLSAPERKIF
EALSDIKRDADEKVLNNSQILNNESYFEQQMVSCVIEHFEDRHHITLTAQAATEINRLIV
KEYLNEFNTGARTW