Protein Info for DZA65_RS03335 in Dickeya dianthicola ME23

Annotation: YggS family pyridoxal phosphate-dependent enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 PF01168: Ala_racemase_N" amino acids 7 to 217 (211 residues), 82.7 bits, see alignment E=1.7e-27 TIGR00044: pyridoxal phosphate enzyme, YggS family" amino acids 16 to 217 (202 residues), 160.5 bits, see alignment E=2.6e-51

Best Hits

KEGG orthology group: K06997, (no description) (inferred from 62% identity to dda:Dd703_2164)

Predicted SEED Role

"Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D7M4 at UniProt or InterPro

Protein Sequence (219 amino acids)

>DZA65_RS03335 YggS family pyridoxal phosphate-dependent enzyme (Dickeya dianthicola ME23)
MNYNAKQVLDNYLTIKNNVVKKSASAKLLAVSKFHGMDKIQPLLDAGHRLFGESRLEESV
DKWSPIRDKYEDLELHFIGGLQSRKIQKIVDFFDVIQSVDRVSIAEKISSSARAICKVQR
IFIQINIGNEPQKNGIPPEKFDVLYNKINEMENIKVEGIMCIPPNEDDVSSYFKKMHNIA
SNFGFSQLSMGMSHDYELALNYKATIVRVGSFIFGERSS