Protein Info for DZA65_RS02770 in Dickeya dianthicola ME23

Annotation: SIR2 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details PF13289: SIR2_2" amino acids 134 to 263 (130 residues), 42.4 bits, see alignment E=3.8e-15

Best Hits

KEGG orthology group: None (inferred from 51% identity to neu:NE2094)

Predicted SEED Role

"FIG036446: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CSY4 at UniProt or InterPro

Protein Sequence (337 amino acids)

>DZA65_RS02770 SIR2 family protein (Dickeya dianthicola ME23)
MSELDYAKQAQRFYQQAPTIILGSGASAAFGLSGMGALATHLLQSIDLSRSDGASKDKWQ
QFSEMLNNGKDLETALHEVRLPADLTEQVVHLTWKLLNPQDIDVFNQSIQQSNFFPLSEL
VSSLFRSALNEINIITTNYDRLAEYAVEQAGHHHYTGFSHGFCRTQKGTEHIRCNRIVKI
LKVHGSLDWFISPLNDIVGYSHLNLIPDNHIPKIVTPGIEKYSATYHEPFRTIINLADNA
IRNATSYLCIGFGFNDEHIQEKLVEKCVRENACITLITHGLTNSARDFLLSGKVKNFLAI
ECGKEHSGSVIYSSEATSPVFVDDDYWSLKGYLKLVC