Protein Info for DZA65_RS02380 in Dickeya dianthicola ME23

Annotation: IclR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 PF09339: HTH_IclR" amino acids 16 to 64 (49 residues), 46.3 bits, see alignment 2.9e-16 PF01614: IclR" amino acids 134 to 258 (125 residues), 109.2 bits, see alignment E=1.4e-35

Best Hits

Swiss-Prot: 60% identical to YIAJ_ECOLI: DNA-binding transcriptional repressor YiaJ (yiaJ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to ddd:Dda3937_02871)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CQ34 at UniProt or InterPro

Protein Sequence (268 amino acids)

>DZA65_RS02380 IclR family transcriptional regulator (Dickeya dianthicola ME23)
MRTVPHGHDKPTGNQSLLRGFLLLEILSNYPNGCPLAHLAGLARLNKSTVHRLLQGLQAC
GYVTPAPAAGSYRLTTRFITVGQTSLAPPEVLRLIAPHLQALNAATGETVNFSRRDGDYC
ILIHKLEPTTGMLRTRAYLGQQMTLFSSAMGKLFLADGTEDALFSYWGRHHAHIRKLTPY
TITDPGHMKREREDVRQRGVAFDREEHEVGVCCMAAPVFDVHRRVKYAISLSLSSAKLRQ
IDEETLLTPLRQTADSLTQALKTLPDDM