Protein Info for DZA65_RS02230 in Dickeya dianthicola ME23

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 transmembrane" amino acids 24 to 47 (24 residues), see Phobius details amino acids 61 to 79 (19 residues), see Phobius details amino acids 91 to 112 (22 residues), see Phobius details amino acids 120 to 140 (21 residues), see Phobius details amino acids 152 to 172 (21 residues), see Phobius details amino acids 179 to 199 (21 residues), see Phobius details amino acids 212 to 232 (21 residues), see Phobius details amino acids 238 to 256 (19 residues), see Phobius details amino acids 276 to 302 (27 residues), see Phobius details amino acids 314 to 332 (19 residues), see Phobius details amino acids 340 to 361 (22 residues), see Phobius details amino acids 367 to 384 (18 residues), see Phobius details amino acids 406 to 430 (25 residues), see Phobius details amino acids 436 to 454 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 28 to 200 (173 residues), 31.1 bits, see alignment E=1.3e-11 PF07690: MFS_1" amino acids 29 to 419 (391 residues), 176.1 bits, see alignment E=1e-55

Best Hits

Swiss-Prot: 67% identical to YEBQ_ECOLI: Uncharacterized transporter YebQ (yebQ) from Escherichia coli (strain K12)

KEGG orthology group: K08169, MFS transporter, DHA2 family, multidrug resistance protein (inferred from 96% identity to ddd:Dda3937_01325)

Predicted SEED Role

"Putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XW23 at UniProt or InterPro

Protein Sequence (464 amino acids)

>DZA65_RS02230 MFS transporter (Dickeya dianthicola ME23)
MNAVVTSQGAGSAVDGLPMPARLGAIFAIAFGIAMAVLDGALVNVALPTIAADFNTSPAS
SIWIVNAYQLAITMTLLSLSSLGDIVGYRRVYLVGLVLFTLMSVVCALADSLPTLTLARI
LQGLAAAALMSVNTALIRLIYPKDKLGRGMAINSLVVAVSTAAGPTIAAGILGVASWQWL
FAINVPFGIVALLLGWRFLPRNDGVRAQRFDAPSALLNALTFGLFFIALGGFAQGQNLWQ
VLGELALTLLVGGYFVRRQLSQSYPLLPVDLLRIPVFALSVGTSVSSFCAQMLAMVSLPF
YFQSALGMNEIETGLLLTPWPLAIMAVAPLAGRWLERVNAGVLCTIGLSLFALGLFSLAW
LPASPGYLDICLRMVLCGIGFGLFQSPNNHTIISAAPRHRSGGASGMLGTARLVGQTAGA
ALVALMFNLFGGQGTHAALITAGVFAALAAVVSGQRISRLAAAP