Protein Info for DZA65_RS02040 in Dickeya dianthicola ME23

Annotation: carbamate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF00696: AA_kinase" amino acids 10 to 282 (273 residues), 88.6 bits, see alignment E=2.9e-29 TIGR00746: carbamate kinase" amino acids 10 to 306 (297 residues), 379.7 bits, see alignment E=4.6e-118

Best Hits

Swiss-Prot: 54% identical to ARCC_SYNY3: Carbamate kinase (arcC) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K00926, carbamate kinase [EC: 2.7.2.2] (inferred from 76% identity to cko:CKO_03556)

Predicted SEED Role

"Carbamate kinase (EC 2.7.2.2)" in subsystem Arginine Deiminase Pathway or Arginine and Ornithine Degradation or MLST or Polyamine Metabolism (EC 2.7.2.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XTC7 at UniProt or InterPro

Protein Sequence (309 amino acids)

>DZA65_RS02040 carbamate kinase (Dickeya dianthicola ME23)
MANPAVIKPTLVVALGGNALLKRGEPLEADIQQHNIIQAARIIAELTEQWNVVLVHGNGP
QVGLLALQNNAYSAVTPYPLDILGAESQGMIGYLLEQALRNTLPQREISTLLTQVEVDPR
DPAFDQPTKYIGPVYQQEYADAIHREKGWTMKADGQHFRRVVPSPQPQQIVESDAIAALI
ARNHLVICTGGGGVPVTRDSNGQLSGVEAVIDKDLSAAMLARQIHADALLILTDADAVYL
DWGKASQQPLHKVTPGDLAGMSFDAGSMGPKIAAACEFVNHCHAVAGIGSLTDGTAILAG
QKGTLIRFA