Protein Info for DZA65_RS01695 in Dickeya dianthicola ME23

Annotation: 4,5-DOPA dioxygenase extradiol

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02900: LigB
  • amino acids 12 to 261 (250 residues), 93.6 bits, E=6.1e-31

Best Hits

Swiss-Prot: 69% identical to YGID_ECOLI: 4,5-DOPA dioxygenase extradiol (ygiD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_00723)

MetaCyc: 69% identical to 4,5-DOPA dioxygenase extradiol (Escherichia coli K-12 substr. MG1655)
Stizolobate synthase. [EC: 1.13.11.29]

Predicted SEED Role

"Uncharacterized protein ygiD"

MetaCyc Pathways

• betalamic acid biosynthesis (2/3 steps found)
• superpathway of betalain biosynthesis (13/27 steps found)

KEGG Metabolic Maps

• Tyrosine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.13.11.29

Sequence Analysis Tools

See A0A385XSF3 at UniProt or InterPro

Protein Sequence (262 amino acids)

>DZA65_RS01695 4,5-DOPA dioxygenase extradiol (Dickeya dianthicola ME23)
MSTSRMPALFLGHGSPMNALDENDYTLAWRKLGETLPRPKAIVAVSAHWYTRGTAVTAMD
KPRTIHDFDGFPQALFDTQYPAPGAPDVAKRVQDLLAPVSVYADNREWGLDHGTWGVLIK
VYPQADIPIVQLSIDGTKPPAYHYELGRKLAALRDEGIMIVASGNVVHNLRMIKWNGDGA
PYGWATAFNDFVRSNLAWQGDAAEHPLVSFMQHNDAALSNPTPDHFLPLLYVLGGWDGQE
PVSTPTDGIVMGSLSMMSVQVG