Protein Info for DZA65_RS01680 in Dickeya dianthicola ME23

Annotation: penicillin-binding protein activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 683 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF04348: LppC" amino acids 44 to 295 (252 residues), 158.6 bits, see alignment E=1.4e-50 amino acids 356 to 677 (322 residues), 276.8 bits, see alignment E=2.1e-86

Best Hits

Swiss-Prot: 87% identical to LPOA_DICC1: Penicillin-binding protein activator LpoA (lpoA) from Dickeya chrysanthemi (strain Ech1591)

KEGG orthology group: K07121, (no description) (inferred from 92% identity to ddd:Dda3937_00720)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CPL4 at UniProt or InterPro

Protein Sequence (683 amino acids)

>DZA65_RS01680 penicillin-binding protein activator (Dickeya dianthicola ME23)
MLPLNSVRTHAGRLIPVMLAALFLAGCPSQAPQGTAPQQHVEGKAGASSDYYLQQMQQSG
DDSKADWQLLAIHALIQEGKLPQANGQLNALSPQLNDKQRQEQRLLLAELAVAQNDLNAA
NSTLAQLDVKSLSPQQQERYYQTQIKAAQNRPSLTMIRAYIGLEPLLQGDAHQRNIDQTW
AALTRLTQQDLGAMVINVDENTLQGWLDLLNLWQTKAQVPTDLQAAIEDWKKRYPRHPAA
KQLPSQLGGTPPVAATQPGENAPVGGNAIALLLPLNGQAQTFANAIQQGFSAAKSGQVSL
AMPAQTAQSASSAATTASPAAPATPTPDISSASSAAPTASPTPLAAATAVPALTTTAAST
IPVKVYDTSNQTLANVIAQAQKDGATTIVGPLLKNEVEQLPRLNPSLNVLALNQPEQVQP
NPNICYFALSPEDEAADAAEFIHKQGKQHPLILAPRGNLGDRVVAAFAKSWQQQSGGVVL
QQRTGGVYDLKQAINSGAGLALNGQPVITATSAPSSSTTVGGLTIPNQAPPIANVTSDGN
VDAVYIIATPDELTLIKPMIDMRNKGALHPALYASSRSYQAGLGPDFRFEMEGLQFSDIP
LLTGASPALMQQVSTQFRNDYSLVRLFAMGMDAWKLASNFAQLHQPGNSLSGATGVLSTS
PDCVVNRKLTWLQFRQGQLVPAS