Protein Info for DZA65_RS01460 in Dickeya dianthicola ME23

Annotation: p-hydroxybenzoic acid efflux pump subunit AaeB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 649 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 54 (19 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 91 to 110 (20 residues), see Phobius details amino acids 116 to 136 (21 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 295 to 316 (22 residues), see Phobius details amino acids 368 to 392 (25 residues), see Phobius details amino acids 404 to 423 (20 residues), see Phobius details amino acids 429 to 446 (18 residues), see Phobius details amino acids 453 to 471 (19 residues), see Phobius details amino acids 483 to 500 (18 residues), see Phobius details amino acids 512 to 529 (18 residues), see Phobius details amino acids 541 to 561 (21 residues), see Phobius details PF04632: FUSC" amino acids 8 to 647 (640 residues), 471.8 bits, see alignment E=6.7e-145 PF13515: FUSC_2" amino acids 22 to 160 (139 residues), 41.5 bits, see alignment E=2.1e-14 PF11744: ALMT" amino acids 59 to 203 (145 residues), 20.9 bits, see alignment E=2.4e-08

Best Hits

Swiss-Prot: 92% identical to AAEB_DICZ5: p-hydroxybenzoic acid efflux pump subunit AaeB (aaeB) from Dickeya zeae (strain Ech586)

KEGG orthology group: None (inferred from 95% identity to ddd:Dda3937_00672)

MetaCyc: 59% identical to aromatic carboxylic acid efflux pump subunit AaeB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-233

Predicted SEED Role

"FUSARIC ACID RESISTANCE PROTEIN FUSB / FUSARIC ACID RESISTANCE PROTEIN FUSC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CK29 at UniProt or InterPro

Protein Sequence (649 amino acids)

>DZA65_RS01460 p-hydroxybenzoic acid efflux pump subunit AaeB (Dickeya dianthicola ME23)
MNSPAFLRLRFAFKLSMAIVLSLVLGFHLQLETPRWAALTAAIVAAGPAFAAGGDPFSGA
IRHRGMLRVIGTFIGCIGALVIIIATVRAPVVMLMLCCLWAGVCVWISSLVKVENAYVFA
LAGYTTLIIIVTSQSAPLRIPQFAVERCSEIVLGIVCAILADLLFSPRSVKQDIDRAVDE
LLVGQYQLLQRCVNGMSKEELDAAWNGLVRKTHAINGMRSVLMMESSRWQGASRRIKTLL
TQSWVMITQACETRLMLQDHPDAVKSAIAMMLEQPADTPAEMQRRLRQLRHLAAAHSRSL
PPTLVSWLAAAASYQLLAKGVKTNVRISQSEAALLDADVPVKASSAETHHAMINGVRTAV
ATGLGCLFWLWTGWTSGSSCMVIIAVVTSLAMRLPNPLMAAKDFLIGSLVALPLGALMFM
LVLPSTQQSLLLLCLSLGGVAFVIGIEVQKRRLGSLGALASTINIVVLSNPMQFNLSQFL
DNAIGQVIGCFLALIVILLIRDNTRDRTERSLLNRFVFGAVSALSTRPARRRENHLPALY
QHLFLLLNLLPGEIGKYRLALSLIMMHQRLRTLELPVSPSLSAFHRQMRATAEQVIEATR
DRSHHFSRLLAQMDEYQHLLRDHQVSDDAIDAVGRLTALLHRHKHALGD