Protein Info for DZA65_RS00280 in Dickeya dianthicola ME23

Annotation: HAMP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 628 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 279 to 299 (21 residues), see Phobius details PF16591: HBM" amino acids 42 to 268 (227 residues), 77.2 bits, see alignment E=2.1e-25 PF00672: HAMP" amino acids 299 to 349 (51 residues), 41.1 bits, see alignment 2.7e-14 PF00015: MCPsignal" amino acids 414 to 568 (155 residues), 190.1 bits, see alignment E=4.4e-60

Best Hits

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_00992)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XRY1 at UniProt or InterPro

Protein Sequence (628 amino acids)

>DZA65_RS00280 HAMP domain-containing protein (Dickeya dianthicola ME23)
MALKFENIKVGRKLGLGFSLILLLTVIIAAVSVRYIETLQGRFEKVIFSNKINDEVNEAR
YYRVLYSISYNPDSIQQNTKHIDNIINLISSIQDKSWRGDYNDKLDNIAKLISQYKERQK
NYTDAIAKKDDVRKSWNLSDSEKPLKQIEQQVAGNLPLQLQLSTLHQKLVTVRYLVRGLL
LSLNSDAEKPLVTALDDAQAALNQFIQALTPEQQAIMAPVVSTLSTYKTQVLAYLPAYQM
EMNQAKQLGETANQLIDNVDKMVYEETAATQNDITNAEWQIAITALITLVLGALIAWYIS
RQITHPLNNTVAIAESIATGDLTISIETTRRDELGMLFGAMAKMKANLHNMIDDIRMGVS
QITTAASEIVTGNNDLAARTESQAASVEETAASMEQLTSTVKQNAANAHQANKLVLEATQ
TAQEGGKLVADVVQTMTDIEGSSKRIAEITSVINSIAFQTNILALNAAVEAARAGEQGRG
FAVVANEVRNLAQRSSQAAKEIEGLISTSVSQVSKGAHLVHNAGKTMQEIVTAVTHVHDI
MGEITVASDEQSRGIAQVNQAIVEMDSTTQQNAALVQQSSAAASSLEEQAVMLSNTVSAF
RLSSTQELMPASHGLPFAGHRQQLSYKH