Protein Info for DZA65_RS00255 in Dickeya dianthicola ME23

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 351 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR03427: ABC transporter periplasmic binding protein, urea carboxylase region" amino acids 25 to 351 (327 residues), 515.6 bits, see alignment E=2.8e-159 PF13379: NMT1_2" amino acids 37 to 251 (215 residues), 34.6 bits, see alignment E=1.9e-12 PF09084: NMT1" amino acids 56 to 242 (187 residues), 44.6 bits, see alignment E=1.7e-15

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 95% identity to ddd:Dda3937_00997)

Predicted SEED Role

"Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4DHD2 at UniProt or InterPro

Protein Sequence (351 amino acids)

>DZA65_RS00255 ABC transporter substrate-binding protein (Dickeya dianthicola ME23)
MKTIQRLLLVCALVLCSAGALAANKPAFKLCWSIYAGWMPWDYAQQQGIIKKWADKYGID
IQFVQVNDYIESVNQYTAGGFDGCAMTNMDALTIPAVGGVDSTALIVGDYSNGNDGILIK
GTNHLTALKGKPINLVQLSVSHYLLARALEKNGMSEKDIKVVNTADADLVAAFGTSEVQS
IVTWNPLLAEAKKQPGSQLAFSSAQIPGEIIDLLVVNTATLKQHPELGKALTGAWYETLQ
VMSGDSSAARQARTFMGQAAGTDLAGFDEQLAATHLFATPKQALEFVQNARLKATMQSVA
EFSFRHGLLGDGALGADMVGVFTPAGLWGNTGNVKLRFSDEFLKLAADNTL