Protein Info for DZA65_RS00035 in Dickeya dianthicola ME23

Annotation: oligopeptidase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 680 PF19310: TOP_N" amino acids 46 to 145 (100 residues), 88.8 bits, see alignment E=2.5e-29 PF01432: Peptidase_M3" amino acids 222 to 677 (456 residues), 574 bits, see alignment E=3.4e-176

Best Hits

Swiss-Prot: 83% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01414, oligopeptidase A [EC: 3.4.24.70] (inferred from 96% identity to ddd:Dda3937_01054)

MetaCyc: 84% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CUY3 at UniProt or InterPro

Protein Sequence (680 amino acids)

>DZA65_RS00035 oligopeptidase A (Dickeya dianthicola ME23)
MTNPLLSSFTLPPFSQIQIEHILPAVQAALDDCRQAVERVVAQPGPFTWDNLCQPLAESD
DRLGRIFSPVSHLNSVKNSPELRSAYEQCLPLLSEYSTWVGQHAGLYHAYRDLHDGQHYA
GLSVAQKKAVDNALRDFELSGIALPPAQQKRYGDIASRLSELGSQFSNNVLDATMGWTKL
ITDANELTGMPESALAAAKALAEAKEQQGWLLTLDIPSYLPVMTYCANQALREEMYRAYV
TRASEQGPNAGKWDNSEVMAETLALRHELAQLLGFANFADKSLATKMAENPQQVLDFLTD
LAKRARPQGEQELAQLHAFAKAQFGVDELNPWDITYYAEQQKQHLYSISDEQLRPYFPEP
RVLEGLFEVVKRIYGITAKERQGVDVWHPEVRFFDLFNDSGELLGSFYLDLYAREHKRGG
AWMDDCAGRLRKANGELQKPVAYLTCNFNRPINGKPALFTHDEVTTLFHEFGHGLHHMLT
RIDTAGVSGINGVPWDAVELPSQFMENWCWEPDALAFISGHYETGAPLPQEMLDKMLAAK
NYQAALFILRQLEFGLFDFRLHAGYDPANGARVLATLAEVKAQVSVVKSPEWNRFPHAFS
HIFAGGYAAGYYSYLWADVLAADAFSRFEEEGIFNRDTGLSFLENILSRGGSEEPMELFK
RFRGREPKLDAMLKHYGIQE