Protein Info for DDA3937_RS21155 in Dickeya dadantii 3937

Annotation: OFA family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 88 to 108 (21 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 179 to 201 (23 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 268 to 289 (22 residues), see Phobius details amino acids 308 to 327 (20 residues), see Phobius details amino acids 333 to 359 (27 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 397 to 418 (22 residues), see Phobius details PF07690: MFS_1" amino acids 28 to 383 (356 residues), 118 bits, see alignment E=4.5e-38 PF13347: MFS_2" amino acids 152 to 388 (237 residues), 33 bits, see alignment E=2.5e-12

Best Hits

KEGG orthology group: K08177, MFS transporter, OFA family, oxalate/formate antiporter (inferred from 100% identity to ddd:Dda3937_01032)

Predicted SEED Role

"oxalate/formate antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SNC7 at UniProt or InterPro

Protein Sequence (435 amino acids)

>DDA3937_RS21155 OFA family MFS transporter (Dickeya dadantii 3937)
MSEIITMQNRTDKEILGFNRWWLFALAFLAMSVISPYEYAWSVIAPHFAKIYGWEPTKIS
LMFSMFVIFQAFGTLPGGIFRDKFGPKAVSVVAGIFSGIGLLVCAFGQELSYNVVLTVWC
IGCFFCGFVYNAAITTCNKWFPDHRNITIGLISAAFSWGALPFIFPIRSIPESAPDSTFF
NVIFIMTAVISGVIIITGLLMKDPPKGWRHSTSSSATKNKVAKRPCEKQYSMGEAMHTWQ
FWVLIASFVLVSASGLTFISNSIKFASAFHFSLTAGTVVTVGMAVTSGLSRVVGGWIADK
IGIDKTMTIFYILCGVFSLVALFLAEAGSATGFISSCIISIFFWGALYSLFASIVGYYYG
EVASGSNYGMLYASAKGLGGIYGGVLSAYLISTYGHPFTIIVSSIMALLSGLILIPLWKH
PPVWKETNGVLITTH