Protein Info for DDA3937_RS20290 in Dickeya dadantii 3937

Annotation: transcription/translation regulatory transformer protein RfaH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 PF02357: NusG" amino acids 3 to 96 (94 residues), 76 bits, see alignment E=1.4e-25 TIGR01955: transcription elongation factor/antiterminator RfaH" amino acids 4 to 159 (156 residues), 207 bits, see alignment E=7.9e-66

Best Hits

Swiss-Prot: 71% identical to RFAH_ECOL6: Transcription antitermination protein RfaH (rfaH) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K05785, transcriptional antiterminator RfaH (inferred from 100% identity to ddd:Dda3937_02070)

Predicted SEED Role

"Transcriptional activator RfaH" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SLH4 at UniProt or InterPro

Protein Sequence (162 amino acids)

>DDA3937_RS20290 transcription/translation regulatory transformer protein RfaH (Dickeya dadantii 3937)
MRAWYLLYCKRGQLLRAKEHLERQDVVCLSPMIALEKIVRGKRTEVSEPLFPNYLFVEFD
PEHIHTTTISSTRGVSHFVRFGNLPALVPQQVIDDLLQHPCATHIDPEMPQPGDQVTITE
GVFSGLQAIYTEPDGEARSMLLLNLLNKQVRQSIDNRQFRKA