Protein Info for DDA3937_RS19630 in Dickeya dadantii 3937

Annotation: lysophospholipid acyltransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 transmembrane" amino acids 198 to 219 (22 residues), see Phobius details PF19576: Acyltransf_2" amino acids 15 to 235 (221 residues), 89.2 bits, see alignment E=3.4e-29 PF01553: Acyltransferase" amino acids 68 to 192 (125 residues), 45.9 bits, see alignment E=7.5e-16 PF13444: Acetyltransf_5" amino acids 322 to 422 (101 residues), 86.3 bits, see alignment E=3.2e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_00352)

MetaCyc: 74% identical to ornithine lipid synthase (Serratia proteamaculans 568)
RXN-12431 [EC: 2.3.2.30]; RXN-12432 [EC: 2.3.2.30, 2.3.1.270]

Predicted SEED Role

"Putative hemolysin"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.270 or 2.3.2.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SJT5 at UniProt or InterPro

Protein Sequence (572 amino acids)

>DDA3937_RS19630 lysophospholipid acyltransferase family protein (Dickeya dadantii 3937)
MFSLDNLLQELAPHRSTPTWQRSLLRSLLFENEFQQFAQRYPHLKGLDLVEQVLDHFSLN
CEMVEGDLENIPSRGPVVLVANHPIGSLDGLALLRTVASVRPDVRVVASQLLSYIEPLKN
LFFSVDNFSNRTRRHQLAAIQEHLAGDGAIIMFPAGEVSRMSLKGIRDGHWHSGFIRMAA
KARAPIVPIHISGRNSNLFYLSSLIYRPLSTLLLVREMFRQRGNRLRFRIGAQIPYPTWS
QGEWQPNDLAARFRRHVYRLGQGKPGCFNGDKPIALPEERTLLKRALETCEALGTTPDGK
KIYLYRRGSEDYVPILRELGRLREISFRAVGEGSGKRRDLDSFDDDYLHLVLWDDRELEI
VGAYRFAPTARLLAEKDISGLYSHSLFQYGEEMAPVLASGIELGRSFIQPKYWGKRGLDY
LWLGIGAYLARYPEYRYLFGPVSLSGSLPSPARDLLIAFYRLHFAPSQALARSRRPYPAS
LPEVLRQFEGDDYQQDLTRLKSMLSNMGCSIPTLYKQYSELCEPGGVQFIDFGLDPDFNN
CVDGLVLVDLQQLKASRHQRYIAPFCNEASVQ