Protein Info for DDA3937_RS19590 in Dickeya dadantii 3937

Annotation: intracellular growth attenuator family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 709 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 202 to 220 (19 residues), see Phobius details amino acids 226 to 245 (20 residues), see Phobius details amino acids 339 to 359 (21 residues), see Phobius details amino acids 652 to 677 (26 residues), see Phobius details PF07095: IgaA" amino acids 1 to 701 (701 residues), 1161.9 bits, see alignment E=0

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_00361)

Predicted SEED Role

"IgaA: a membrane protein that prevents overactivation of the Rcs regulatory system"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SJS5 at UniProt or InterPro

Protein Sequence (709 amino acids)

>DDA3937_RS19590 intracellular growth attenuator family protein (Dickeya dadantii 3937)
MRTILIILAVLFACLIAVGGIIGYLMYRRLLFAKRLPVTPSGHRQLTASERIAIERYLAM
SHLDGPVSSSVSVASPRLPRLLPGNRVYPITHSITRYGLSTDAPNKWRYYIDTQEIHLPA
RWEQYITQNNEIELIKTRSIPLVVSLNGHSLTEFINEMDSSAGVDIPGEQASIRPEVHEH
TELVAIRRETLEEHAVHRSRGLRETGVLSLAFLLLVFSLTSPLAMLPWLAGAACLMAGWG
CWQLFRPPSQKELREVHCLHGTPQCMGLFSDASQSQIGNVSLGNIDLIYPPHWQPYIGYD
LGRKTDVDIYLTRQVVRQGHYLSLHNEVKFFPLQQWGKNAVLAVGALLSLILLLTSVPLD
LPLKLSLAWVQGTSSVKVTQVEDLERMPLHIGDKLQVRGAGMCYVPPINLNPTSSRASAF
APFDCAAIYWNKAAPLPLPESDTIEKTTALQKTVNEQLHPAASDNQVSSQLADAIQKSGM
ILLNNFSDIVLKTDALCEKEEDCTRLKNALINLGNAKNWELLVKRARSGALKGMSVVLRP
VSAESLDSLVKNATDEFYSREIITASNSLNSPPPGGFLIRSDEGRQFVNHQMPTTPLRDF
PPQEQWQELQRLSSMLLHTPFEANGVITQLSIDANGTRHISLHSEPDAVTMWRSLGACLL
LLAFSVILILNLVLLLVKRRRSQQRIANIQQYYARHLVPETPVATAMYG