Protein Info for DDA3937_RS18495 in Dickeya dadantii 3937

Annotation: oxidative stress defense protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF04402: SIMPL" amino acids 33 to 236 (204 residues), 170 bits, see alignment E=4.4e-54

Best Hits

Swiss-Prot: 67% identical to YGGE_ECO57: Uncharacterized protein YggE (yggE) from Escherichia coli O157:H7

KEGG orthology group: K09807, hypothetical protein (inferred from 100% identity to ddd:Dda3937_00410)

Predicted SEED Role

"Protein of unknown function DUF541"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SH47 at UniProt or InterPro

Protein Sequence (242 amino acids)

>DDA3937_RS18495 oxidative stress defense protein (Dickeya dadantii 3937)
MKLKVLALTTLLGIGLSSMTVQAGNELPSGPHIVTSGAASVDATPDIARLAIEVSVSSKD
VADAKKQVDERVAQYFAFLDKSGIDKKDINAANLRTQPEYDYLKNGGSVLKGYRAIRQVE
VTLRQLDKLNELLDGALKSGLNEIRAVELGVSNPDVYREQARKKAIEQATQQAQSLASGF
NAALGPVYSIRYHVANYQPVPVARMFKTADMVAQSEVSQTYEQQTIHFDDQVDVVFELQR
AP