Protein Info for DDA3937_RS18490 in Dickeya dadantii 3937

Annotation: LysR family transcriptional regulator ArgP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 TIGR03298: transcriptional regulator, ArgP family" amino acids 5 to 293 (289 residues), 372.4 bits, see alignment E=6.8e-116 PF00126: HTH_1" amino acids 7 to 64 (58 residues), 65.5 bits, see alignment E=3.4e-22 PF03466: LysR_substrate" amino acids 93 to 289 (197 residues), 53.9 bits, see alignment E=1.7e-18

Best Hits

Swiss-Prot: 95% identical to ARGP_PECCP: HTH-type transcriptional regulator ArgP (argP) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 100% identity to ddd:Dda3937_00409)

Predicted SEED Role

"Chromosome initiation inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SH46 at UniProt or InterPro

Protein Sequence (297 amino acids)

>DDA3937_RS18490 LysR family transcriptional regulator ArgP (Dickeya dadantii 3937)
MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENLFGQPLLVRTIPPRPT
EQGQKLLALLHQVELLEEEWLGNENSSETPLLLSLAVNADSLATWLLPALQPVLVDSPIR
LNLQVEDETRTQERLRRGEVVGAVSIQPQPLPSCLVDKLGALDYLFVASPGFANRYFPNG
VTRSALLRAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMI
PHLQIERELANGELIDLTPGLFQRRMLYWHRFAPESRMMRQVTDALLTHGHQVLRQS