Protein Info for DDA3937_RS17970 in Dickeya dadantii 3937

Annotation: protein transport protein HofC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 transmembrane" amino acids 167 to 193 (27 residues), see Phobius details amino acids 214 to 232 (19 residues), see Phobius details amino acids 253 to 272 (20 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details PF00482: T2SSF" amino acids 65 to 187 (123 residues), 112.5 bits, see alignment E=6.7e-37 amino acids 270 to 390 (121 residues), 81.2 bits, see alignment E=3.2e-27

Best Hits

Swiss-Prot: 42% identical to HOFC_ECOLI: Protein transport protein HofC homolog (hofC) from Escherichia coli (strain K12)

KEGG orthology group: K02505, protein transport protein HofC (inferred from 100% identity to ddd:Dda3937_02241)

Predicted SEED Role

"Type IV fimbrial assembly protein PilC" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SG61 at UniProt or InterPro

Protein Sequence (401 amino acids)

>DDA3937_RS17970 protein transport protein HofC (Dickeya dadantii 3937)
MAVQKLYYWQALRSDGEFCAGERIGTSRNEIYQYLLELGYQPLRLKTGQYLTPRYWRGPQ
LSVIIRQLATLLQAGLPLLDALDLLGRQHEKAGWRCLLQEIRQQVAQGRALSEVLADYPA
AFPMMCSSLVAVGELTGKLDDCCARLANYQENQRQLTGKVIKALRYPAFVIAVGLLVALL
MLTLVLPEFAGLYASFDAPLPWLTRMMLRLSDALSRHGMLLVTLPVVILLGYRQIRRQKV
EWQKREQRLLLKLPLLSTLVRGHCLSQIFHTLAMTQQAGLTLPSGLSAAATLNNPVYRQS
LAEIKSRLEQGIPLGQAIHDDPLLYPAPCHQLVSVGEETGALDQLFARLAGWYENHTRQF
ADTLTQTLEPLLLVIVGGLVGTLVIAMYLPIFQLGNVLAGA