Protein Info for DDA3937_RS17710 in Dickeya dadantii 3937

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 PF00356: LacI" amino acids 3 to 45 (43 residues), 59.1 bits, see alignment 7.4e-20 PF00532: Peripla_BP_1" amino acids 112 to 284 (173 residues), 63.1 bits, see alignment E=7.5e-21 PF13377: Peripla_BP_3" amino acids 174 to 340 (167 residues), 117.9 bits, see alignment E=1.3e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_03076)

Predicted SEED Role

"putative LacI family HTH-type transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SFC5 at UniProt or InterPro

Protein Sequence (358 amino acids)

>DDA3937_RS17710 LacI family DNA-binding transcriptional regulator (Dickeya dadantii 3937)
MATLKDIADRAGVSISTVSRVLNGTAPISAKVRQQIMAIATEQGYPLHKASKTADNPEPL
RHIMLATPRNLMLESDLNLVSLTLINRLKTLCQQRNIRLSPFVGEPDSINEQQLLQALRG
GRESGILIVNDDHPTLLNAVAESGVPAVLINGEDPTMRLNTVMPANHYSAAAAVRYLIAQ
GHRRILHLTWHSRQTIRERERGYRDALVEAGIPLDERLILSLPDFQPLTARDALLGWLAR
HPDRLGVTAIFCAADNQAIGVAEALNQHGLRVPDDMSVMGMDDILPLDMLPLALTTVHLP
FEEMARAALHLLTQQLLPTQSLGVAQRIELAGHLKIRDSVRGITPPAGSTAAENDSNS