Protein Info for DDA3937_RS17585 in Dickeya dadantii 3937

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 536 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 292 to 311 (20 residues), see Phobius details PF02743: dCache_1" amino acids 80 to 269 (190 residues), 52.4 bits, see alignment E=5.2e-18 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 366 to 524 (159 residues), 164.8 bits, see alignment E=7.4e-53 PF00990: GGDEF" amino acids 368 to 521 (154 residues), 144.2 bits, see alignment E=3.2e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_03463)

Predicted SEED Role

"GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SF99 at UniProt or InterPro

Protein Sequence (536 amino acids)

>DDA3937_RS17585 GGDEF domain-containing protein (Dickeya dadantii 3937)
MRIKKLIQINLLHLILFISLASMFVTLLNSYLTFYHVQKKLLIEQAVKVNSSYSSKLSVT
VDNFFSMSEEQLSYSAKLIASHIQSGNLRPLQAELQRIHQLSHAFNSMVVVTEHGQIIAA
SPTSLNLTGITLTSNRHLTTLREKRFFISAPYTSLSGNYIIFISYPIADDVGNYLGYIGG
SLYLNSRRILNEFMNTQFSNDSFNTYVIDKEGTIIYHRDTGQIGKKINDSHILSSIANQD
KGSFMMPDEQGILSPASFIRTQKAGWIIITQQSFHSLEEALNDVMISVLKQGTPLGILTL
LALSILAYYIAKPLRQLSKSASSMDQLGVISKIRAVKAWYLEVEQLKRVLLMGTVLLHKR
IGRLSSEAHTDPLSGMLNRRGMQESMEEIRSEYKKISVIAIDIDHFKVINDSFGHDVGDE
VIRKLSQQIRKNFRKTDLVCRIGGEEFLILLPGADIHVATVIAERLRNNVANTVYMPGYR
HHQVTISIGVTTFNPQKSALDIAIKTADNALYKAKNGGRNQVVVEYLSDDISLAQH