Protein Info for DDA3937_RS17345 in Dickeya dadantii 3937

Annotation: bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 732 transmembrane" amino acids 43 to 61 (19 residues), see Phobius details amino acids 262 to 279 (18 residues), see Phobius details amino acids 415 to 439 (25 residues), see Phobius details PF01553: Acyltransferase" amino acids 15 to 139 (125 residues), 70.7 bits, see alignment E=1.1e-23 PF00501: AMP-binding" amino acids 235 to 570 (336 residues), 196.3 bits, see alignment E=7.6e-62

Best Hits

Swiss-Prot: 81% identical to AAS_PECCP: Bifunctional protein Aas (aas) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K05939, acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC: 2.3.1.40 6.2.1.20] (inferred from 100% identity to ddd:Dda3937_02592)

MetaCyc: 68% identical to fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase (Escherichia coli K-12 substr. MG1655)
RXN-5741 [EC: 6.2.1.47]; 6.2.1.- [EC: 6.2.1.47]; Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase. [EC: 6.2.1.47, 2.3.1.40]

Predicted SEED Role

"2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) / Acyl-[acyl-carrier-protein] synthetase (EC 6.2.1.20)" (EC 2.3.1.40, EC 6.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.40 or 6.2.1.20 or 6.2.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SEG4 at UniProt or InterPro

Protein Sequence (732 amino acids)

>DDA3937_RS17345 bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase (Dickeya dadantii 3937)
MIYTFLRWALKQLYRIQITGDESGFRQSKILITPNHVSFLDGVLMALFLPVQSKPVFAVY
SSITDRWFMRWLKPYIDFLPLDPSKPLAIKQLIRLVEQGRPVVVFPEGRITVTGSLMKIY
GGAAFVAARSGATVVPVRIEGPEFTHFGRLGGVLRRRLFPQISLHFLPPAKLPMPVAPSA
RERRELAGEALHRIMMDARMAVRPRHTLYQAFLAACGRYGYHSPCIEDINLKEDSYHGLL
KKSLGVSRILQRFTGEREHVGLLLPNATVTAAAILGASLGSRVPAMLNYTAGAKGIQSAM
SAARIKTIVTSRQFLEKGKLTHLPQQVKEANWVYLEDLKDTVTLSDKLWILFHLLFPLRA
MRPQQPDDAAIVLFTSGSEGNPKGVVHTHNSLTANVEQIRTVADFTPRDRFMSALPLFHA
FGLTVGLLTPLMTGARVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGHYARFAHPYDF
ARLRYVVAGAEKLSERVRTVWQDKFGIRILEGYGVTECAPVVAINVPMACKLHSVGRLLP
GIESRLIPVPGIHHGGRLQLRGPNVMKGYLRVENPGELELPAAENELGQREANWYDTGDI
VDLDAQGFCTIVGRVKRFAKLAGEMVSLESVEQLANQVSPQTQHAASARSDSSKGEALVL
FTTDAGLTRDSLLTQARQSGMPELAVPRDIRYLKELPLLGSGKPDFVTLRQLAEQPADGA
DDVSDAQPEHDA