Protein Info for DDA3937_RS17300 in Dickeya dadantii 3937

Annotation: YggS family pyridoxal phosphate-dependent enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 TIGR00044: pyridoxal phosphate enzyme, YggS family" amino acids 11 to 237 (227 residues), 309.2 bits, see alignment E=8.6e-97 PF01168: Ala_racemase_N" amino acids 14 to 237 (224 residues), 77.9 bits, see alignment E=4.8e-26

Best Hits

Swiss-Prot: 74% identical to PLPHP_ECO57: Pyridoxal phosphate homeostasis protein (yggS) from Escherichia coli O157:H7

KEGG orthology group: K06997, (no description) (inferred from 100% identity to ddd:Dda3937_02601)

Predicted SEED Role

"Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SEF5 at UniProt or InterPro

Protein Sequence (244 amino acids)

>DDA3937_RS17300 YggS family pyridoxal phosphate-dependent enzyme (Dickeya dadantii 3937)
MTISTVTTSVVQQNLQDVRQRISAAAERCGRAPEEITLLAVSKTKPVSAIEEAIAAGQRA
FGENYVQEGVDKVRHFQAAQPDTQLEWHFIGPLQSNKSRLVAEHFDWCHTIDRLRIAQRL
SEQRPAHLPPLNVLLQVNISQEQSKSGILARDLSGLAASVAHLPNLRLRGLMAIPAPETD
HARQLAVFRQMTELFLQLKADYGTLDTLSMGMTDDMAAAIEAGSTLVRIGTAIFGARDYS
SPAS