Protein Info for DDA3937_RS17265 in Dickeya dadantii 3937

Annotation: nitric oxide-sensing transcriptional repressor NsrR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 141 TIGR00738: Rrf2 family protein" amino acids 1 to 128 (128 residues), 127 bits, see alignment E=2.2e-41 PF02082: Rrf2" amino acids 3 to 130 (128 residues), 132.5 bits, see alignment E=1.1e-42

Best Hits

Swiss-Prot: 92% identical to NSRR_PECAS: HTH-type transcriptional repressor NsrR (nsrR) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K13771, Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor (inferred from 100% identity to ddd:Dda3937_02608)

Predicted SEED Role

"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SEE8 at UniProt or InterPro

Protein Sequence (141 amino acids)

>DDA3937_RS17265 nitric oxide-sensing transcriptional repressor NsrR (Dickeya dadantii 3937)
MQLTSFTDYGLRALIYMASLPEGKMTSISEVTEVYGVSRNHMVKIINQLSRAGLVMAVRG
KNGGIRLGRDPSTIRIGDVVRELEPLSLVNCSKEFCHITSACRLKQVLQQAVQNFLKELD
NYTLADMVEENPPLYKLLLVE