Protein Info for DDA3937_RS16845 in Dickeya dadantii 3937

Annotation: methionine ABC transporter ATP-binding protein MetN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 TIGR02314: D-methionine ABC transporter, ATP-binding protein" amino acids 1 to 343 (343 residues), 645.9 bits, see alignment E=6.7e-199 PF00005: ABC_tran" amino acids 21 to 169 (149 residues), 133.1 bits, see alignment E=1.7e-42 PF09383: NIL" amino acids 268 to 339 (72 residues), 75.5 bits, see alignment E=3.7e-25

Best Hits

Swiss-Prot: 85% identical to METN3_PECAS: Methionine import ATP-binding protein MetN 3 (metN3) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K02071, D-methionine transport system ATP-binding protein (inferred from 100% identity to ddd:Dda3937_03917)

MetaCyc: 84% identical to L-methionine/D-methionine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
RXN0-4522 [EC: 7.4.2.11]; 7.4.2.11 [EC: 7.4.2.11]; TRANS-RXN-383 [EC: 7.4.2.11]; TRANS-RXN0-510 [EC: 7.4.2.11]; TRANS-RXN0-511 [EC: 7.4.2.11]

Predicted SEED Role

"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SDI2 at UniProt or InterPro

Protein Sequence (343 amino acids)

>DDA3937_RS16845 methionine ABC transporter ATP-binding protein MetN (Dickeya dadantii 3937)
MIELINITKVFQQKGRAVTALDDVTLRVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEG
KVLIDGKDLMSLSESQLTRTRRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPASEIKQR
VHQLLDLVGLSDKHDAYPANLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSIL
ELLKDINRRLGLTILLITHEMDVVKRICDQVAVISDGKLIEQDTVSEVFSHPKTPLAQKF
IQSTLHLDIPDDYQQRLSATPRPNSVPLLRMEFTGQSVDAPLLSEVARTFNVNNNIISAQ
MDYAGGVKFGIMLAEMHGQETDTQAAIAFLQQHHVNIEVLGYV