Protein Info for DDA3937_RS16725 in Dickeya dadantii 3937

Annotation: glycine betaine/L-proline ABC transporter permease ProW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 transmembrane" amino acids 146 to 167 (22 residues), see Phobius details amino acids 172 to 191 (20 residues), see Phobius details amino acids 198 to 221 (24 residues), see Phobius details amino acids 241 to 268 (28 residues), see Phobius details amino acids 320 to 341 (22 residues), see Phobius details amino acids 352 to 372 (21 residues), see Phobius details PF00528: BPD_transp_1" amino acids 212 to 379 (168 residues), 98.5 bits, see alignment E=2e-32

Best Hits

Swiss-Prot: 100% identical to OUSW_DICD3: Glycine betaine/choline transport system permease protein OusW (ousW) from Dickeya dadantii (strain 3937)

KEGG orthology group: K02001, glycine betaine/proline transport system permease protein (inferred from 100% identity to ddd:Dda3937_00900)

MetaCyc: 79% identical to glycine betaine ABC transporter membrane subunit ProW (Escherichia coli K-12 substr. MG1655)
RXN-8638 [EC: 7.6.2.9]; 7.4.2.- [EC: 7.6.2.9]

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SCY2 at UniProt or InterPro

Protein Sequence (406 amino acids)

>DDA3937_RS16725 glycine betaine/L-proline ABC transporter permease ProW (Dickeya dadantii 3937)
MTDTTQNPWEEDQAPDQAAAANHSHAAATSGEHAAAAGSSGTPAQTDPWAASSSAPAGNT
PAPDNAADAWSNAPPPAASDVHQSAADWLNSTPTPTQEHFNLMDPFRHTLVPLDRWVTEG
IDWLVLHFRPLFQGIRVPVDMILTSFQQLLTGLPAPVAILVFSLLAWQVSSFGMGVATLL
SLVAIGAIGAWSQAMVTLALVLTALFFCVIIGLPLGIWLAHSDRAARIVRPLLDAMQTTP
AFVYLIPIVMLFGIGNVPGVVVTIIFALPPIIRLTILGIRQVPADLVEAAQSFGASPRQM
LFKVQLPLAMPTIMAGINQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLASIGGV
GIVILAIILDRLTQSLGRDARSRGNRHWYHHGPLGLLARPFIKSRA