Protein Info for DDA3937_RS16705 in Dickeya dadantii 3937

Annotation: NCS1 family nucleobase:cation symporter-1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 transmembrane" amino acids 38 to 86 (49 residues), see Phobius details amino acids 118 to 142 (25 residues), see Phobius details amino acids 155 to 177 (23 residues), see Phobius details amino acids 189 to 207 (19 residues), see Phobius details amino acids 229 to 250 (22 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 312 to 334 (23 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 376 to 400 (25 residues), see Phobius details amino acids 429 to 447 (19 residues), see Phobius details amino acids 453 to 472 (20 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 30 to 461 (432 residues), 281.8 bits, see alignment E=5.1e-88

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 96% identity to ddc:Dd586_3277)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SCX7 at UniProt or InterPro

Protein Sequence (494 amino acids)

>DDA3937_RS16705 NCS1 family nucleobase:cation symporter-1 (Dickeya dadantii 3937)
MPENMTPAGTTPAHYSPRLCNEDLAPTRVQSWSWYNIFSFWMSDVHSMGGYVVAASFFTL
GLASWQVLLCLLAGICIVQLCANLVAKPSQLSGVPYAVMCRQSFGVFGANIPAVIRGLIA
FAWYGIQTYLAASALMLVLLKFVPSLTPLTTSHWLGLSTLGWLCFGVMWLLQAMVFWHGM
SAIKRFIDIAGPAVYVVMLALAGWIVYKTGLENISFTLGSKSLSSGEQVWQMITATALVV
SYFSGPLLNFGDFSRYAKSMQEIRRGNRWGLPFNFLLFSIVTVVIVSGTQSLFGQMITDP
IETVSRVGNSVAVALGLLTMIVATIGINIVANFVSPAFDFSNCAPQRISFRTGGMIAAVG
SVLLTPWNLFNSPELIHYTLDVLGAFIGPLFGILLADFYLIKGGKVDVDALFNDTPSGRY
WYRNGINPNAVLALLPSVAIGLVISFVPDWHEVANFSWFIGVALGAGSYRYLARREKAVT
PAATGLSGLVLGKE