Protein Info for DDA3937_RS16640 in Dickeya dadantii 3937

Annotation: alanine--glyoxylate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 100% identity to ddd:Dda3937_00917)

MetaCyc: 84% identical to ureidoglycine aminotransferase subunit (Klebsiella pneumoniae pneumoniae MGH 78578)
RXN-12221

Predicted SEED Role

"Serine--pyruvate aminotransferase (EC 2.6.1.51) / L-alanine:glyoxylate aminotransferase (EC 2.6.1.44)" in subsystem Photorespiration (oxidative C2 cycle) or Pyruvate Alanine Serine Interconversions or Serine-glyoxylate cycle (EC 2.6.1.44, EC 2.6.1.51)

MetaCyc Pathways

glycine biosynthesis III (1/1 steps found)
L-serine biosynthesis II (3/4 steps found)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.44 or 2.6.1.51

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SCW4 at UniProt or InterPro

Protein Sequence (414 amino acids)

>DDA3937_RS16640 alanine--glyoxylate aminotransferase family protein (Dickeya dadantii 3937)
MHNDLFAQINPPHRLLMGPGPINADPRVLRAMASQLVGQYDPAMTGYMNQVMALYRQLFR
TDNRWTMLVDGTSRAGIEAILVSAIRPGDRVLVPVFGRFGHLLCEVARRCRADVHTIEVP
WGEVFTPDQIEDAIKRVKPRLLLTVQGDTSTTMLQPLAELGAICRRHDVLFYTDATASFG
GNPLETDAWGLDAVSAGLQKCLGGPSGSSPITLSPGMEAVIRQRKCVEQGIRTTDHQDGD
DEMIYSNYFDLGMIMDYWGPERLNHHTEATSMLFAARECARVILEEGLDACIARHQLHGR
ALLAGIEGMGLQPYGDIANKMSNVLGVVIPQGIHGEQVRKLLLEDFAIEVGTSFGPLQGK
IWRVGTMGYNARKDCVMQTLTALEAVLNRLGFRSAQGAALQAAWDVYDAARAPA